Prescription antibiotic + pore-clearing gel. In the BenzaClin Phase 3 trial (Leyden et al., Cutis 2001), patients saw a 67% drop in inflammatory acne lesions at 11 weeks.
licensed physician reviews your intake. If clindamycin/BPO is right for you, they write the prescription.
licensed pharmacy. Apply a thin layer to clean skin twice daily. Message your care team anytime to adjust strength or cadence.
about 10 seconds per use
licensed pharmacy (not a research chemical, not gray market)
acnes (the bacteria) and unclogs pores (the plug)
BenzaClin Phase 3 (Leyden JJ, et al. Cutis. 2001;68(2 Suppl):12-18). Randomized, double-blind, vehicle-controlled, 11 weeks. Population: adolescents and adults with mild-to-moderate acne vulgaris (inf
Clindamycin is an antibiotic — it kills Cutibacterium acnes, the bacteria that turns a clogged pore into a red, painful pimple. Benzoyl peroxide is a keratolytic — it dissolves the dead skin and oil plug inside the pore so the antibiotic can reach the bacteria, and so new pimples don't form. Using BPO alongside clindamycin also lowers the chance of bacteria becoming antibiotic-resistant, which is why dermatologists rarely prescribe clindamycin by itself anymore.
Important information about Clindamycin / Benzoyl Peroxide safety and side effects.
Yes — BPO alone is OTC. Clindamycin is prescription-only, and the combination is what drove the 67% result. BPO by itself reduced lesions less in the same trial.
Yes, BPO bleaches fabric. Use white washcloths and a white pillowcase, or let it fully dry before bed.
The first 1–2 weeks usually involve some dryness and peeling. If it's severe, message your care team — they can drop you to once-daily or every-other-day until your skin adjusts.
Not for this. A U.S. licensed physician reviews your history online and writes the prescription if it's appropriate. If your acne is severe or has a hormonal pattern, they'll tell you and refer out.
30-day money-back on your first month. Cancel anytime after.
Both ingredients increase sun sensitivity. Use SPF 30+ on your face daily.
Real reviews from verified ArgoMD patients.
I've been using Clindamycin / Benzoyl Peroxide for 3 months and the improvement in my skin is remarkable. My dermatologist is impressed with my progress.
After trying countless products, Clindamycin / Benzoyl Peroxide from ArgoMD actually delivered results. The physician guidance on how to introduce it gradually was key.
My skin has never looked better. Clindamycin / Benzoyl Peroxide paired with the protocol my ArgoMD doctor recommended has made a visible difference that friends notice.
Your health and safety are our top priorities.