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Ezetimibe

The FDA-approved pill that blocks your gut from absorbing cholesterol. In post-heart-attack patients already on a statin, adding ezetimibe cut major cardiovascular events from 34.7% to 32.7% over 7 years (IMPROVE-IT, NEJM 2015).

4.9 (verified patients)
Monthly
$39
/month
$39 $65

$1.3 per daily dose

Check If Ezetimibe Is Right For You — 3-Minute Consult
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How It Works

1

Answer questions about your cholesterol, statins you've tried, and family history.

Takes about 3 minutes.

2

A U.S.-licensed physician reviews your file.

If ezetimibe fits, they write the script.

3

Your FDA-approved generic ezetimibe ships from a licensed U.S.

pharmacy. Same molecule your cardiologist would prescribe. Refills auto-ship monthly.

Why Patients Choose

One 10mg tablet a day.

No injections. No timing tricks. Take it whenever.

Works in a different place than statins

your gut, not your liver — so it stacks with a statin or stands alone if statins wrecked your muscles.

In IMPROVE-IT (18,144 post-ACS patients on simvastatin, 7-year follow-up), adding ezetimibe cut the rate of death, MI, stroke, unstable angina, or revascularization from 34.7% to 32.7%.

LDL drop of roughly 15-20% on monotherapy in clinical trials.

Real numbers your next lipid panel will show.

Same molecule as Zetia.

Generic price.

Clinical Evidence

Clinical Trial

IMPROVE-IT (Cannon et al., NEJM 2015): 18,144 adults hospitalized for acute coronary syndrome, randomized to simvastatin 40mg + ezetimibe 10mg vs. simvastatin 40mg + placebo. Over 7 years, the combo g

7%
IMPROVE-IT (Cannon et al., NEJM 2015): 18,144 adults hospita

How

Your small intestine has a protein called NPC1L1 that grabs cholesterol from your food and from bile and pulls it into your bloodstream.

Ezetimibe sits on NPC1L1 and blocks it. About half the cholesterol that would have crossed into your blood goes out in your stool instead. Your liver senses the drop and pulls more LDL out of circulation. That's how the number on your lipid panel goes down.

Safety Information

Important information about Ezetimibe safety and side effects.

Important Safety Information

Warnings

Common Side Effects

Frequently Asked Questions

Can I take it with my statin? — Yes — that's the most-studied use case. Tell our physician what statin and dose you're on. They may want to recheck liver enzymes. What are the side effects? — In trials, the most common were diarrhea, fatigue, and muscle pain, mostly mild. Stop and call us if you get yellowing of the skin/eyes or severe muscle pain. Do I need to fast or take it with food? — No. Once a day, with or without food. Can I cancel? — Yes, anytime, from your account. No call, no retention pitch. Will my insurance or HSA cover this? — FSA/HSA cards work at checkout. We don't bill insurance — the cash price is usually cheaper than a copay anyway.

What Patients Are Saying

Real reviews from verified ArgoMD patients.

RM
Robert M.
Verified Patient

My cardiologist recommended I add Ezetimibe and my numbers have never been better. The convenience of getting it delivered monthly is a game changer.

March 2026
DL
Diane L.
Verified Patient

I've been on Ezetimibe for 6 months now. My latest labs showed significant improvement in my cardiovascular markers. The ArgoMD team is always available when I have questions.

February 2026
TW
Thomas W.
Verified Patient

Switched to ArgoMD for my Ezetimibe prescription and couldn't be happier. Better price, same medication, and the physician check-ins give me confidence in my treatment plan.

January 2026

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If you're not completely satisfied with your first month, contact us within 30 days for a full refund. No questions asked.

Safety & Compliance

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You've been reading longevity Twitter for two years and buying questionable powders off Telegram. Ezetimibe is the boring version — FDA-approved since 2002, on every cardiologist's prescription pad, $28-$40 a month, shipped from a real U.S. pharmacy with a real physician's name on the script. Start the 3-minute consult.

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