Bioidentical progesterone in a capsule you take at night. Same molecule your ovaries make — binds the progesterone receptor and GABA-A, which is why it tends to make you sleepy (and that's the point at bedtime).
$1.5 per daily dose
See if a doctor will prescribe it for you — 3-minute intaketakes about 3 minutes.
board-certified physician reviews your history and decides if micronized progesterone is appropriate. If it's not safe for you, they'll tell you and refund the visit.
Take one capsule at bedtime. Labs are repeated at 3 months so your doctor can adjust the dose.
progesterone's GABA-A activity has a sedating effect, which is why it's dosed at bedtime.
this is the on-label use and the reason most prescribers add it.
No injections, no creams, no timing around meals.
KEEPS trial (Harman et al., Annals of Internal Medicine, 2014): 727 healthy women within 3 years of menopause. Oral micronized progesterone 200 mg for 12 days/month, paired with low-dose estrogen, imp
It does two things that matter here:
It binds the progesterone receptor in the uterus, which keeps the uterine lining from overgrowing when you're also taking estrogen.
Its metabolite, allopregnanolone, binds the GABA-A receptor in the brain — the same receptor benzodiazepines hit. That's why it makes you drowsy and why you take it at night, not in the morning.
Same molecule, different delivery.
Important information about Micronized Progesterone safety and side effects.
No. It's a prescription from a U.S.-licensed physician, filled by a U.S.-licensed pharmacy, shipped to your door. You can verify the pharmacy license.
No. Micronized progesterone (USP) is the same molecule your ovaries produce, FDA-approved as Prometrium. We're not talking about a custom "bioidentical hormone cocktail."
Most people get drowsy (that's why it's at night). Some get breast tenderness or bloating in the first few weeks. If side effects don't settle, your physician adjusts the dose or stops it.
Maybe, maybe not. If you have a uterus and you're on estrogen, you need progesterone to protect the lining. If you're not on estrogen, your doctor will tell you whether progesterone alone makes sense for your situation.
If you have a history of breast cancer, liver disease, blood clots, or undiagnosed vaginal bleeding, the physician will not prescribe it. The intake screens for this.
Real reviews from verified ArgoMD patients.
Starting Micronized Progesterone through ArgoMD changed everything for me. My energy, mood, and sleep all improved within weeks. The physician monitoring with regular labs is reassuring.
After years of feeling off, Micronized Progesterone brought me back to myself. The ArgoMD team took time to understand my symptoms and found the right dose for me.
The convenience of having Micronized Progesterone delivered monthly plus physician oversight makes this so much better than my old clinic experience. Highly recommend.
Your health and safety are our top priorities.