A GPR109A agonist that raised HDL 20–30% and lowered triglycerides 20–50% in lipid trials. Prescription strength, not the OTC version that gives you a face flush and not much else.
$1.3 per daily dose
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pharmacy in labeled bottles. Take one tablet at bedtime. We re-check your liver enzymes and lipid panel at 6–8 weeks.
no injections, no daily flush spike if dosed correctly
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What niacin ER has been shown to do, with honest bounds: Cardiovascular events: AIM-HIGH (NEJM 2011, n=3,414) tested niacin ER added to simvastatin in patients with established cardiovascular disease
That slows the release of free fatty acids into the blood. With less raw material reaching the liver, the liver makes less VLDL, which means lower triglycerides and lower LDL — and HDL goes up. The "extended release" part spreads the dose out so the flush is smaller and the liver gets a steadier, lower peak than instant-release niacin.
Important information about Niacin Extended Release safety and side effects.
You can. The OTC version is fine for a mild flush and a B-vitamin top-up. It is not the same as 500–2000 mg prescription extended-release dosed at bedtime with a liver-enzyme check at 6 weeks. The risk with high-dose niacin isn't the flush — it's hepatotoxicity. That's why this one is prescription-only and why we re-check your labs.
AIM-HIGH showed niacin added on top of a statin didn't further reduce events in already well-treated patients. It did not show niacin fails to change lipids. Your physician will tell you straight up whether niacin makes sense for your specific lipid panel.
No — it's a histamine-like skin reaction in the first few weeks and it fades. Take at bedtime with a low-fat snack. Aspirin 30 minutes before helps. We coach you through this.
Probably a warm flush the first 1–3 weeks. You won't feel HDL going up. You'll see it on the lab report at week 6–8.
No. This is an FDA-approved generic medication dispensed by a licensed U.S. pharmacy. Not compounded. Not gray market.
Real reviews from verified ArgoMD patients.
My cardiologist recommended I add Niacin Extended Release and my numbers have never been better. The convenience of getting it delivered monthly is a game changer.
I've been on Niacin Extended Release for 6 months now. My latest labs showed significant improvement in my cardiovascular markers. The ArgoMD team is always available when I have questions.
Switched to ArgoMD for my Niacin Extended Release prescription and couldn't be happier. Better price, same medication, and the physician check-ins give me confidence in my treatment plan.
Your health and safety are our top priorities.
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