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Tadalafil — Prescription ED Treatment

PDE5 inhibitor that relaxes penile smooth muscle for up to 36 hours per dose. In the Brock 2002 Phase 3 trial (n=1,112 men with ED), 81% of intercourse attempts on 20mg were successful vs. 35% on placebo.

4.9 (verified patients)
Monthly
$39
/month
$39 $65

$1.3 per daily dose

Check If You Qualify — 3-Minute Health Intake
Prescription from a Licensed U.S. Pharmacy Not a research chemical. Not gray market. Legally prescribed and fulfilled.
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Physician Guided
FSA/HSA Eligible
Cancel Anytime

How It Works

1

Answer health questions online (takes about 3 minutes).

You'll cover heart history, current meds (especially nitrates), and ED specifics.

2

A board-certified U.S.

physician reviews your intake. If tadalafil is safe for you, they write the prescription. If it's not, they tell you why and what to do instead.

3

Your prescription ships from a licensed U.S.

pharmacy in plain packaging. Refills auto-ship monthly. Cancel anytime from your dashboard.

Why Patients Choose

Up to 36 hours of effect per dose (Brock 2002, J Urol

20mg dose, n=1,112)

81% of intercourse attempts successful on 20mg vs.

35% on placebo (Brock 2002)

Daily 2.5mg or 5mg option for men who want it always on, or 10mg/20mg as needed

Same active ingredient as Cialis, prescribed by a U.S.

physician, dispensed by a licensed U.S. pharmacy

One consult fee, no doctor's office visit, no pharmacy counter

Clinical Evidence

Clinical Trial

Porst H et al., Eur Urol 2003: Effect detectable at 36 hours post-dose in men with mild-to-moderate ED. Note: trial populations were men diagnosed with ED. Results in men without diagnosed ED have not

81%
Brock GB et al., J Urol 2002 (Phase 3, n=1,112 men with ED o

How

Tadalafil blocks the enzyme PDE5. PDE5 normally breaks down cGMP, a molecule that tells the smooth muscle in your penis to relax. With PDE5 blocked, cGMP sticks around longer, blood flows in more easily during arousal, and an erection becomes possible. You still need to be aroused — tadalafil does not cause an erection on its own. The reason it lasts 36 hours and sildenafil lasts 4-6 is the molecule's half-life

about 17.5 hours vs. about 4.

Safety Information

Important information about Tadalafil safety and side effects.

Important Safety Information

Warnings

Common Side Effects

Frequently Asked Questions

Yes. Tadalafil is the generic active ingredient in brand Cialis. FDA approved the generic in 2018.

No. Prescribed by a licensed U.S. physician, dispensed by a licensed U.S. pharmacy. You get a real Rx label with your name on it.

No. The intake is asynchronous text. A U.S.-licensed physician reviews it. If they need more info, they message you.

30-day money-back on your first month. If you're not satisfied, email support within 30 days for a full refund.

Tell the physician every medication you're on. Tadalafil is contraindicated with any nitrate (nitroglycerin, isosorbide) — combining them can drop your blood pressure to dangerous levels. The intake screens for this.

No. Cash pay, no insurance billing. Ships in plain packaging with no product name on the outside.

What Patients Are Saying

Real reviews from verified ArgoMD patients.

JR
John R.
Verified Patient

Tadalafil from ArgoMD works reliably every time. The discreet shipping and easy refills make the whole experience stress-free.

March 2026
MK
Mark K.
Verified Patient

Switched to ArgoMD for my Tadalafil prescription after my insurance changed. Better price, same great results, and the physician consult was thorough.

February 2026
DW
Daniel W.
Verified Patient

The convenience of having Tadalafil delivered to my door plus the physician oversight gives me confidence. It works exactly as expected.

January 2026

30-Day Money-Back Guarantee

If you're not completely satisfied with your first month, contact us within 30 days for a full refund. No questions asked.

Safety & Compliance

Your health and safety are our top priorities.

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Board-Certified Physicians
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