Weekly injection that copies two of your body's appetite hormones at once (GLP-1 + GIP). In SURMOUNT-1 (Jastreboff et al., NEJM 2022), adults with obesity lost 22.5% of body weight at 72 weeks on the 15mg dose — vs 2.4% on placebo.
$1.3 per daily dose
See if you qualify — 2-minute intake (BMI 27+, age 18+)If approved, your prescription ships from a licensed 503A compounding pharmacy Pre-filled syringes, alcohol swabs, and a sharps container arrive within 5-7 business days in temperature-controlled packaging. Step 3 — Inject once a week into your belly, thigh, or upper arm Most patients do it Sunday morning. The injection takes about 10 seconds. Message your care team anytime about side effects or dose changes.
SURMOUNT-1 — Jastreboff AM et al., NEJM 2022 (N=2,539 adults with obesity, no type 2 diabetes, 72 weeks): • 5mg/week: 16.0% • Placebo: 2.4% SURPASS-2 — Frias JP et al., NEJM 2021 (N=1,879 adults with
GLP-1 and GIP.
Tirzepatide mimics both — which is why it outperformed semaglutide on weight loss and blood sugar in the SURPASS-2 head-to-head trial.
Important information about Tirzepatide safety and side effects.
Most patients see 2–4 lbs in the first month, then 1–2 lbs per week as the dose steps up. Full SURMOUNT-1 results were measured at 72 weeks (~17 months). How is the dose increased? You start at 2.5mg/week for 4 weeks. Your physician then steps you up — 5mg, 7.5mg, 10mg, 12.5mg, 15mg — over 5–6 months, based on how you tolerate it and how much you're losing. How do I inject it? Pinch a fold of skin on your belly, thigh, or upper arm. Press the pre-filled syringe in. Takes ~10 seconds. We include video instructions and a sharps container. Do I need bloodwork to start? Not to start. Your physician may request labs if you have a history of thyroid disease, pancreatitis, or kidney disease. Who cannot take tirzepatide? Anyone with a personal or family history of medullary thyroid carcinoma (MTC) or MEN 2 syndrome. Do not use during pregnancy, breastfeeding, or while trying to conceive. Stop at least 2 months before attempting pregnancy. What are the common side effects? Nausea, diarrhea, vomiting, constipation, abdominal pain, indigestion, injection site reactions. Most are mild and improve over the first 4–8 weeks.
Real reviews from verified ArgoMD patients.
Down 47 lbs in 5 months on Tirzepatide. The process was so easy — filled out the form online, doctor approved me same day, and my medication arrived 2 days later. The weekly injection is way easier than I expected.
After trying every diet imaginable, Tirzepatide finally gave me the tool I needed. I've lost 32 lbs and my energy is through the roof. The care team checks in regularly which keeps me accountable.
The onboarding was seamless. I was nervous about the injection but it's so easy. I've lost 38 lbs in 4 months and my doctor says my blood work has improved across the board.
Your health and safety are our top priorities.