0
Prescription Required (Rx) U.S. Licensed Physicians FDA-Approved Molecule FSA/HSA Eligible Cancel Anytime

Tretinoin (Prescription Retinoid)

Binds retinoic acid receptors to speed cell turnover. In a 24-week trial (Weinstein 1991, n=251), patients with photodamaged skin showed measurable reduction in fine wrinkles and hyperpigmentation versus vehicle.

4.9 (verified patients)
Monthly
$39
/month
$39 $65

$1.3 per daily dose

Start the 3-minute eligibility check
Prescription from a Licensed U.S. Pharmacy Not a research chemical. Not gray market. Legally prescribed and fulfilled.
Free Shipping
Physician Guided
FSA/HSA Eligible
Cancel Anytime

How It Works

1

Answer the medical intake (about 3 minutes).

Skin history, pregnancy status, current actives, sun exposure.

2

A U.S. licensed physician reviews your file. If tretinoin fits, they write the prescription. If it doesn't, they tell you why and suggest an alternative

you don't get charged.

3

Your pharmacy ships the tube to your door.

Apply a pea-sized amount at night, 20 minutes after washing. Care team answers questions by message for the life of the script.

Why Patients Choose

Reduction in fine wrinkles and mottled pigmentation at 24 weeks (Weinstein et al., 1991, photodamaged adults, tretinoin 0.05% cream vs vehicle).

Reduction in inflammatory and non-inflammatory acne lesion counts at 12 weeks (Leyden et al., J Am Acad Dermatol 1995, mild-to-moderate acne).

Once-nightly application.

No injections, no in-office visits.

Same molecule dermatologists prescribe in-office

without the $250 derm visit.

Clinical Evidence

Clinical Trial

Acne: Leyden JJ et al., J Am Acad Dermatol 1995 — tretinoin reduced acne lesion counts vs vehicle in mild-to-moderate acne patients over 12 weeks. Note: Results above apply to the study populations an

05%
Photoaging: Weinstein GD et al., Arch Dermatol 1991 — 0.05%

How

Tretinoin is all-trans retinoic acid.

It binds RAR receptors in skin cells, which tells those cells to divide and shed faster. Faster turnover means clogged pores empty out (acne), pigmented cells slough off (tone), and the dermis builds new collagen over months (fine lines).

Safety Information

Important information about Tretinoin safety and side effects.

Important Safety Information

Warnings

Common Side Effects

Frequently Asked Questions

Retinol is roughly 1/20th as potent as tretinoin and has to convert in the skin. Tretinoin is the active form — it's why it's prescription-only.

Most people get dryness, flaking, or redness in the first 2–6 weeks. We start most patients at 0.025% every other night to manage it. Message your physician and they'll adjust.

Your script is written by a U.S. licensed physician who reviews your intake. Same controlled substance laws, same pharmacy regulations as your local clinic.

30-day refund on your first month. Cancel anytime after.

Do not use tretinoin. Flag this on intake and the physician will decline the script.

What Patients Are Saying

Real reviews from verified ArgoMD patients.

NR
Nicole R.
Verified Patient

I've been using Tretinoin for 3 months and the improvement in my skin is remarkable. My dermatologist is impressed with my progress.

March 2026
KT
Katie T.
Verified Patient

After trying countless products, Tretinoin from ArgoMD actually delivered results. The physician guidance on how to introduce it gradually was key.

February 2026
MW
Michelle W.
Verified Patient

My skin has never looked better. Tretinoin paired with the protocol my ArgoMD doctor recommended has made a visible difference that friends notice.

January 2026

30-Day Money-Back Guarantee

If you're not completely satisfied with your first month, contact us within 30 days for a full refund. No questions asked.

Safety & Compliance

Your health and safety are our top priorities.

FDA-Registered Pharmacy
Board-Certified Physicians
HIPAA Compliant
Secure Shipping

Check eligibility in 3 minutes. If a physician approves you, your first tube ships within 3-5 business days. If not, you pay nothing.

Get Started