A daily vaginal insert. DHEA is converted to estrogen and androgen inside the vaginal cells themselves — so the hormones act locally, not systemically. In the Phase 3 trial (Portman DJ et al., Menopause 2018), postmenopausal women using 6.5 mg nightly for 12 weeks saw significant improvement in painful sex versus placebo.
No office visit.
physician reviews your history and decides if vaginal DHEA is appropriate for you.
pharmacy. Insert one ovule nightly.
Serum estradiol stayed within the normal postmenopausal range in the trial.
No daily pill, no patch, no cream to measure.
physician handles the prescription and ongoing oversight.
Phase 3 trial — Portman DJ et al., Menopause 2018. 558 postmenopausal women, ages 40–80, with moderate-to-severe painful sex due to vulvovaginal atrophy. After 12 weeks of nightly 6.5 mg vaginal DHEA:
That rebuilds the vaginal lining, restores lubrication, and reduces pain during sex. Because the conversion happens in the cell, serum estrogen in the Portman trial stayed within the normal postmenopausal range.
Important information about Vaginal DHEA safety and side effects.
No. DHEA is a precursor. Vaginal cells convert it locally; serum estradiol stayed within the normal postmenopausal range in the Portman trial.
Yes. Prasterone is an FDA-approved Rx (brand: Intrarosa). A licensed U.S. physician writes the prescription. A U.S. pharmacy fills it.
No. The intake and physician review are online.
30-day money-back guarantee on your first month. Cancel anytime after.
Vaginal DHEA was not studied in women with a history of hormone-sensitive cancers. Disclose your history in the intake — the physician will decide.
In the Phase 3 trial, statistically significant improvements showed up by week 12. Some patients report symptom changes earlier; the trial endpoint was 12 weeks.
Real reviews from verified ArgoMD patients.
Starting Vaginal DHEA through ArgoMD changed everything for me. My energy, mood, and sleep all improved within weeks. The physician monitoring with regular labs is reassuring.
After years of feeling off, Vaginal DHEA brought me back to myself. The ArgoMD team took time to understand my symptoms and found the right dose for me.
The convenience of having Vaginal DHEA delivered monthly plus physician oversight makes this so much better than my old clinic experience. Highly recommend.
Your health and safety are our top priorities.